Cysteine Residues in <i>Helicobacter pylori</i> Adhesin HopQ are Required for CEACAM–HopQ Interaction and Subsequent CagA Translocation

Cysteine Residues in <i>Helicobacter pylori</i> Adhesin HopQ are Required for CEACAM–HopQ Interaction and Subsequent CagA Translocation

<b> </b>Attachment to the host gastric mucosa is a key step in <i>Helicobacter pylori </i>infection. Recently, a novel adhesin, HopQ, was shown to bind distinct host CEACAM proteins&#8212;an interaction that was found to be essential for the translocation of CagA, a key v...

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Bibliographic Details
Main Authors: Youssef Hamway, Karin Taxauer, Kristof Moonens, Victoria Neumeyer, Wolfgang Fischer, Verena Schmitt, Bernhard B. Singer, Han Remaut, Markus Gerhard, Raquel Mejías-Luque
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Microorganisms
Subjects:
bacterial adhesion
caga delivery
ceacam1
<i>helicobacter pylori</i>
hopq
host-pathogen interactions
dsb-like proteins
Online Access:https://www.mdpi.com/2076-2607/8/4/465

Internet

https://www.mdpi.com/2076-2607/8/4/465

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