Role of Hormones in the Regulation of RACK1 Expression as a Signaling Checkpoint in Immunosenescence

Role of Hormones in the Regulation of RACK1 Expression as a Signaling Checkpoint in Immunosenescence

Immunosenescence defines the decline in immune function that occurs with aging. This has been associated, at least in part, with defective cellular signaling via protein kinase C (PKC) signal transduction pathways. Our data suggest reduced PKC activation and consequently reduced response to lipopoly...

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Bibliographic Details
Main Authors: Marco Racchi, Erica Buoso, Melania Ronfani, Melania M. Serafini, Marilisa Galasso, Cristina Lanni, Emanuela Corsini
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:International Journal of Molecular Sciences
Subjects:
aging
immunosenescence
signal transduction
protein kinase C
transcriptional regulation
cortisol
dehydroepiandrosterone
glucocorticoid receptors.
Online Access:https://www.mdpi.com/1422-0067/18/7/1453

Internet

https://www.mdpi.com/1422-0067/18/7/1453

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