Inhibition of Erbb2 by Trastuzumab Induces Oxidative Stress Markers in HER2 Positive Breast Cancer Cell Lines

Human epidermal growth factor receptor2 (HER2) amplification occurs in approximately 30% of breast cancers that associated with a faster rate of growth and a poorer prognosis. Trastuzumab is FDA-approved humanized monocholonal antibody that targets the extracellular domain of HER2. In present study...

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Bibliographic Details
Main Authors: Zahra Mohammadi Abgarmi, Abbas Sahebghadam Lotfi, Saeid Abroun, Masoud Soleimani, Shahla Moahammad Ganji
Format: Article
Language:English
Published: Amber Publication 2018-03-01
Series:Journal of Research in Medical and Dental Science
Subjects:
Online Access:https://www.jrmds.in/articles/inhibition-of-erbb2-by-trastuzumab-induces-oxidative-stress-markers-in-her2-positive-breast-cancer-cell-lines.pdf