C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection

C5aR1 Activation Drives Early IFN-γ Production to Control Experimental Toxoplasma gondii Infection

Toxoplasma gondii (T. gondii) is a parasite infecting animals and humans. In intermediate hosts, such as humans or rodents, rapidly replicating tachyzoites drive vigorous innate and adaptive immune responses resulting in bradyzoites that survive within tissue cysts. Activation of the innate immune s...

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Bibliographic Details
Main Authors: Daria Briukhovetska, Birte Ohm, Fabian T. Mey, Julio Aliberti, Marie Kleingarn, Markus Huber-Lang, Christian M. Karsten, Jörg Köhl
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
complement
C5a
C5a receptor 1
Toxoplasma gondii
dendritic cell
NK cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01397/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01397/full

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