The homeobox gene MEIS1 is methylated in BRAF (p.V600E) mutated colon tumors.

The homeobox gene MEIS1 is methylated in BRAF (p.V600E) mutated colon tumors.

Development of colorectal cancer (CRC) can occur both via gene mutations in tumor suppressor genes and oncogenes, as well as via epigenetic changes, including DNA methylation. Site-specific methylation in CRC regulates expression of tumor-associated genes. Right-sided colon tumors more frequently ha...

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Bibliographic Details
Main Authors: Ashwin A Dihal, Arnoud Boot, Eddy H van Roon, Melanie Schrumpf, Arantza Fariña-Sarasqueta, Marta Fiocco, Eliane C M Zeestraten, Peter J K Kuppen, Hans Morreau, Tom van Wezel, Judith M Boer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244575/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244575/?tool=EBI

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