IFITM3 Rs12252-C Variant Increases Potential Risk for Severe Influenza Virus Infection in Chinese Population

IFITM3 Rs12252-C Variant Increases Potential Risk for Severe Influenza Virus Infection in Chinese Population

Background: Interferon Inducible Transmembrane 3 (IFITM3) is a key factor in interferon pathway and it involves host's immune response against multiple viruses. IFITM3 rs12252-C was associated with severe influenza virus infection in several studies, however whether this association is universa...

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Bibliographic Details
Main Authors: Yang Pan, Peng Yang, Tao Dong, Yi Zhang, Weixian Shi, Xiaomin Peng, Shujuan Cui, Daitao Zhang, Guilan Lu, Yimeng Liu, Shuangsheng Wu, Quanyi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
influenza
interferon inducible transmembrane 3
single nucleotide polymorphism
severe acute respiratory infection
genetic susceptibility
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00294/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00294/full

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