Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve

Ingestion of Lactobacillus intestinalis and Lactobacillus reuteri causes depression- and anhedonia-like phenotypes in antibiotic-treated mice via the vagus nerve

Abstract Background The brain–gut–microbiota axis plays a role in the pathogenesis of stress-related disorders such as depression. In this study, we examined the effects of fecal microbiota transplantation (FMT) in mice with antibiotic-treated microbiota depletion. Methods The fecal microbiota was o...

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Bibliographic Details
Main Authors: Siming Wang, Tamaki Ishima, Jiancheng Zhang, Youge Qu, Lijia Chang, Yaoyu Pu, Yuko Fujita, Yunfei Tan, Xingming Wang, Kenji Hashimoto
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Neuroinflammation
Subjects:
Anhedonia
Antibiotic
Depression
Gut microbiota
Vagus nerve
Online Access:http://link.springer.com/article/10.1186/s12974-020-01916-z

Internet

http://link.springer.com/article/10.1186/s12974-020-01916-z

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