CircRNAs: A new perspective of biomarkers in the nervous system

Circular RNAs (circRNAs) are a class of newly-identified non-coding RNA that lack 5’ (cap) and 3’ (polyadenylation) ends and are linked by a covalent bond to form a closed loop structure. In comparison to linear RNAs, circRNAs are more resistant to exonuclease RNase R-mediated degradation with a muc...

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Bibliographic Details
Main Authors: Yun Ma, Yixuan Liu, Zhisheng Jiang
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220304431