Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression

The loss of tumour suppressor gene function is a hallmark of malignant transformation and can occur by a variety of genetic and/or epigenetic alterations. We have previously characterised p38δ mitogen-activated protein kinase (MAPK) as a tumour suppressor in oesophageal squamous cell carcinoma (OESC...

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Bibliographic Details
Main Authors: Carol O' Callaghan, Liam J. Fanning, Orla P. Barry
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/7/4/0881