Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance

<p>Abstract</p> <p>Activation of oncogenes is generally associated with the induction of DNA damage response (DDR) signaling, which acts as a barrier to tumor progression. In this review we will present an overview of the DDR associated with oncogenic activation of Myc, with specia...

Full description

Bibliographic Details
Main Authors: Campaner Stefano, Amati Bruno
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Cell Division
Subjects:
Myc
ATR
Online Access:http://www.celldiv.com/content/7/1/6