Chimeric Antigen Receptor beyond CAR-T Cells

<b> </b>Chimeric antigen receptors (CAR) are genetically engineered receptors that can recognise specific antigens and subsequently activate downstream signalling. Human T cells engineered to express a CAR, also known as CAR-T cells, can target a specific tumour antigen on the cell surfa...

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Bibliographic Details
Main Authors: Vicky Mengfei Qin, Criselle D’Souza, Paul J Neeson, Joe Jiang Zhu
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/3/404