Efficacy and safety of short-term use of a pelubiprofen CR and aceclofenac in patients with symptomatic knee osteoarthritis: A double-blinded, randomized, multicenter, active drug comparative, parallel-group, phase IV, non-inferiority clinical trial

Introduction At present, information about clinical efficacy and adverse events of controlled release (CR) form of pelubiprofen, a prodrug of 2-arylopropionic acid with relatively selective effects on cyclooxygenase-2 activity, remains scarce. In this study, we sought to determine non-inferiority of...

Full description

Bibliographic Details
Main Authors: Joung Youp Shin, Moon Jong Chang, Myung Ku Kim, Seung-Baik Kang, Kang-Il Kim, Hee Gon Park, Sahnghoon Lee, Sung-Hwan Kim, Seung-Beom Han, Han Jun Lee, Young-Wan Moon, Jae-Doo Yoo, Yuanyuan Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523996/?tool=EBI