Combination of EZH2 inhibitor and BET inhibitor for treatment of diffuse intrinsic pontine glioma

Combination of EZH2 inhibitor and BET inhibitor for treatment of diffuse intrinsic pontine glioma

Abstract Background Diffuse intrinsic pontine glioma is an infiltrative, often high-grade glioma of the brainstem that is not amenable to surgical resection. The current treatment of DIPG by radiation therapy showed dramatically improvement of patient’s condition, however, the tumor recurs rapidly....

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Bibliographic Details
Main Authors: Yaqin Zhang, Weijie Dong, Junying Zhu, Lizhu Wang, Xinjian Wu, Hong Shan
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Cell & Bioscience
Subjects:
DIPG
EZH2 inhibitor
BET inhibitor
Epigenetics
Tumor therapy
Online Access:http://link.springer.com/article/10.1186/s13578-017-0184-0

Internet

http://link.springer.com/article/10.1186/s13578-017-0184-0

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