Dual inhibition of sodium–glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction

Abstract Background Inhibiting both type 1 and 2 sodium–glucose linked cotransporter (SGLT1/2) offers the potential to not only increase glucosuria beyond that seen with selective SGLT2 inhibition alone but to reduce glucose absorption from the gut and to thereby also stimulate glucagon-like peptide...

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Bibliographic Details
Main Authors: Kim A. Connelly, Yanling Zhang, Jean-François Desjardins, Kerri Thai, Richard E. Gilbert
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cardiovascular Diabetology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12933-018-0741-9