Dual inhibition of sodium–glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction
Abstract Background Inhibiting both type 1 and 2 sodium–glucose linked cotransporter (SGLT1/2) offers the potential to not only increase glucosuria beyond that seen with selective SGLT2 inhibition alone but to reduce glucose absorption from the gut and to thereby also stimulate glucagon-like peptide...
Main Authors: | Kim A. Connelly, Yanling Zhang, Jean-François Desjardins, Kerri Thai, Richard E. Gilbert |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
|
Series: | Cardiovascular Diabetology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12933-018-0741-9 |
Similar Items
-
Reduction in the incidence of myocardial infarction with sodium–glucose linked cotransporter-2 inhibitors: evident and plausible
by: Richard E. Gilbert, et al.
Published: (2019-01-01) -
Myocardial reserve in patients with myocardial infarction: the role of clinical and functional parameters in its assessment
by: A. P. Ivanov, et al.
Published: (2005-10-01) -
Sodium–glucose cotransporters: Functional properties and pharmaceutical potential
by: Ryuhei Sano, et al.
Published: (2020-07-01) -
Metformin Therapy Effects on the Expression of Sodium-Glucose Cotransporter 2, Leptin, and SIRT6 Levels in Pericoronary Fat Excised from Pre-Diabetic Patients with Acute Myocardial Infarction
by: Celestino Sardu, et al.
Published: (2021-07-01) -
PREDICTIVE VALUE OF ECHOCARDIOGRAPHY IN POST MYOCARDIAL INFARCTION SETTING. PART 1
by: P. V. Krikunov, et al.
Published: (2017-12-01)