trans-10,cis-12 CLA promotes osteoblastogenesis via SMAD mediated mechanism in bone marrow mesenchymal stem cells

The inverse relationship between osteoblast and adipocyte differentiation in bone marrow mesenchymal stem cells has been linked to overall bone mass. It has previously been reported that conjugated linoleic acid (CLA) inhibits adipogenesis via a peroxisome-proliferator activated receptor-γ (PPARγ) m...

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Bibliographic Details
Main Authors: Jonggun Kim, Yooheon Park, Yeonhwa Park
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Journal of Functional Foods
Subjects:
CLA
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614001388