A bow-tie genetic architecture for morphogenesis suggested by a genome-wide RNAi screen in Caenorhabditis elegans.

During animal development, cellular morphogenesis plays a fundamental role in determining the shape and function of tissues and organs. Identifying the components that regulate and drive morphogenesis is thus a major goal of developmental biology. The four-celled tip of the Caenorhabditis elegans ma...

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Bibliographic Details
Main Authors: Matthew D Nelson, Elinor Zhou, Karin Kiontke, Hélène Fradin, Grayson Maldonado, Daniel Martin, Khushbu Shah, David H A Fitch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3048373?pdf=render