Secretagogin Regulates Insulin Signaling by Direct Insulin Binding
Summary: Secretagogin (SCGN) is a β-cell enriched, secretory/cytosolic Ca2+-binding protein with unknown secretory regulation and functions. Recent findings suggest that SCGN deficiency correlates with compromised insulin response and diabetes. However, the (patho)physiological SCGN-insulin nexus re...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-11-01
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Series: | iScience |
Online Access: | http://www.sciencedirect.com/science/article/pii/S258900421930447X |