GOLM1 Stimulation of Glutamine Metabolism Promotes Osteoporosis via Inhibiting Osteogenic Differentiation of BMSCs

GOLM1 Stimulation of Glutamine Metabolism Promotes Osteoporosis via Inhibiting Osteogenic Differentiation of BMSCs

Background/Aims: Bone marrow mesenchymal stem cells (BMSCs) play an essential role in osteoporosis. However, the molecular mechanisms and the involvement of glutamine metabolism in osteogenic BMSCs differentiation and osteoporosis remain largely unclear. In this study, we investigated the role of Go...

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Bibliographic Details
Main Authors: Guangsi Shen, Hong Zhang, Peng Jia, Guangfei Li, Xiao Wang, Xiaozhong Zhou, Youjia Xu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Osteoporosis
BMSCs
GOLM1
mTOR
Glutamine metabolism
Online Access:https://www.karger.com/Article/FullText/494872

Internet

https://www.karger.com/Article/FullText/494872

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