Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study

Hematologic toxicity in BRCA1 and BRCA2 mutation carriers during chemotherapy: A retrospective matched cohort study

Abstract Women who inherit a BRCA1 or BRCA2 mutation have an increased risk of breast cancer. Preliminary evidence suggests they may also have defects in bone marrow function. To test this hypothesis, we conducted a multicenter, retrospective, matched cohort study, comparing women with localized bre...

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Bibliographic Details
Main Authors: Allison H. West, Hayley Knollman, James Dugan, Donald Hedeker, Elisabeth A. Handorf, Sarah M. Nielsen, Lisa C. Bealin, Lindsay G. Goldblatt, Heather Willems, Mary B. Daly, Anosheh Afghahi, Olufunmilayo I. Olopade, Peter J. Hulick, Elena Shagisultanova, Dezheng Huo, Elias Obeid, Jane E. Churpek
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Cancer Medicine
Subjects:
BRCA1
BRCA2
breast cancer
hematologic toxicity
hereditary breast and ovarian cancer syndrome
neutropenic fever
Online Access:https://doi.org/10.1002/cam4.2471

Internet

https://doi.org/10.1002/cam4.2471

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