Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca2+ Signaling in Endothelial Cells

The mechanisms by which the microtubule cytoskeleton regulates the permeability of endothelial barrier are not well understood. Here, we demonstrate that microtubule-associated end-binding protein 3 (EB3), a core component of the microtubule plus-end protein complex, binds to inositol 1,4,5-trisphos...

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Bibliographic Details
Main Authors: Melissa Geyer, Fei Huang, Ying Sun, Stephen M. Vogel, Asrar B. Malik, Colin W. Taylor, Yulia A. Komarova
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715005847