RstA Is a Major Regulator of Clostridioides difficile Toxin Production and Motility

Clostridioides difficile is an anaerobic, gastrointestinal pathogen of humans and other mammals. C. difficile produces two major toxins, TcdA and TcdB, which cause the symptoms of the disease, and forms dormant endospores to survive the aerobic environment outside the host. A recently discovered reg...

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Bibliographic Details
Main Authors: Adrianne N. Edwards, Brandon R. Anjuwon-Foster, Shonna M. McBride
Format: Article
Language:English
Published: American Society for Microbiology 2019-03-01
Series:mBio
Subjects:
Online Access:https://doi.org/10.1128/mBio.01991-18