Hyperglycemia Alters the Structure and Hemodynamics of the Developing Embryonic Heart

Congenital heart defects (CHDs) represent the most common form of human birth defects; approximately one-third of heart defects involve malformations of the outflow tract (OFT). Maternal diabetes increases the risk of CHD by 3–5 fold. During heart organogenesis, little is known about the effects of...

Full description

Bibliographic Details
Main Authors: Taylor B. Lawson, Devon E. Scott-Drechsel, Venkat Keshav Chivukula, Sandra Rugonyi, Kent L. Thornburg, Monica T. Hinds
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:http://www.mdpi.com/2308-3425/5/1/13