IL-9 induces VEGF secretion from human mast cells and IL-9/IL-9 receptor genes are overexpressed in atopic dermatitis.

IL-9 induces VEGF secretion from human mast cells and IL-9/IL-9 receptor genes are overexpressed in atopic dermatitis.

Interleukin 9 (IL-9) has been implicated in mast cell-related inflammatory diseases, such as asthma, where vascular endothelial growth factor (VEGF) is involved. Here we report that IL-9 (10-20 ng/ml) induces gene expression and secretion of VEGF from human LAD2. IL-9 does not induce mast cell degra...

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Bibliographic Details
Main Authors: Nikolaos Sismanopoulos, Danae A Delivanis, Konstantinos D Alysandratos, Asimenia Angelidou, Magdalini Vasiadi, Anastasia Therianou, Theoharis C Theoharides
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3297631?pdf=render

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http://europepmc.org/articles/PMC3297631?pdf=render

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