Anacardic acid, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549 [v1; ref status: indexed, http://f1000r.es/o7]
Objective and design: The histone acetylation processes, which are believed to play a critical role in the regulation of many inflammatory genes, are reversible and regulated by histone acetyltransferases (HATs), which promote acetylation, and histone deacetylases (HDACs), which promote deacetylatio...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2013-03-01
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Series: | F1000Research |
Subjects: | |
Online Access: | http://f1000research.com/articles/2-78/v1 |