Anacardic acid, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549 [v1; ref status: indexed, http://f1000r.es/o7]

Anacardic acid, a histone acetyltransferase inhibitor, modulates LPS-induced IL-8 expression in a human alveolar epithelial cell line A549 [v1; ref status: indexed, http://f1000r.es/o7]

Objective and design: The histone acetylation processes, which are believed to play a critical role in the regulation of many inflammatory genes, are reversible and regulated by histone acetyltransferases (HATs), which promote acetylation, and histone deacetylases (HDACs), which promote deacetylatio...

Full description

Bibliographic Details
Main Authors: Tetsuo Yasutake, Hiroo Wada, Manabu Higaki, Masuo Nakamura, Kojiro Honda, Masato Watanabe, Haruyuki Ishii, Shigeru Kamiya, Hajime Takizawa, Hajime Goto
Format: Article
Language:English
Published: F1000 Research Ltd 2013-03-01
Series:F1000Research
Subjects:
Genetics of the Immune System
Immunomodulation
Medical Genetics
Online Access:http://f1000research.com/articles/2-78/v1

Internet

http://f1000research.com/articles/2-78/v1

Similar Items