First report of elevated monocyte-platelet aggregates in healthy children.

Platelets are subcellular fragments which circulate in blood and have well established roles in thrombosis and haemostasis in adults. Upon activation, platelets undergo granule exocytosis and express P-Selectin on the cell membrane which binds a ligand on monocytes, leading to monocyte-platelet aggr...

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Bibliographic Details
Main Authors: Christina Yip, Vera Ignjatovic, Chantal Attard, Paul Monagle, Matthew D Linden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23826296/pdf/?tool=EBI