Prefrontal Lobe Brain Reserve Capacity with Resistance to Higher Global Amyloid Load and White Matter Hyperintensity Burden in Mild Stage Alzheimer's Disease.

Amyloid deposition and white matter lesions (WMLs) in Alzheimer's disease (AD) are both considered clinically significant while a larger brain volume is thought to provide greater brain reserve (BR) against these pathological effects. This study identified the topography showing BR in patients...

Full description

Bibliographic Details
Main Authors: Ya-Ting Chang, Chi-Wei Huang, Nai-Ching Chen, Kun-Ju Lin, Shu-Hua Huang, Yen-Hsiang Chang, Shih-Wei Hsu, Wen-Neng Chang, Chun-Chung Lui, Che-Wei Hsu, Chiung-Chih Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4752238?pdf=render