Nck2 promotes human melanoma cell proliferation, migration and invasion <it>in vitro </it>and primary melanoma-derived tumor growth <it>in vivo</it>
<p>Abstract</p> <p>Background</p> <p>Nck1 and Nck2 adaptor proteins are involved in signaling pathways mediating proliferation, cytoskeleton organization and integrated stress response. Overexpression of Nck1 in fibroblasts has been shown to be oncogenic. Through the ye...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-10-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/11/443 |