Nck2 promotes human melanoma cell proliferation, migration and invasion <it>in vitro </it>and primary melanoma-derived tumor growth <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Nck1 and Nck2 adaptor proteins are involved in signaling pathways mediating proliferation, cytoskeleton organization and integrated stress response. Overexpression of Nck1 in fibroblasts has been shown to be oncogenic. Through the ye...

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Bibliographic Details
Main Authors: Picard-Cloutier Aude, Ismaïl Salma, Dusseault Julie, Labelle-Côté Mélissa, Siegel Peter M, Larose Louise
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/443