Flk1+ and VE-cadherin+ endothelial cells derived from iPSCs recapitulates vascular development during differentiation and display similar angiogenic potential as ESC-derived cells.

Induced pluripotent stem (iPS) cells have emerged as a source of potentially unlimited supply of autologous endothelial cells (ECs) for vascularization. However, the regenerative function of these cells relative to adult ECs and ECs derived from embryonic stem (ES) cells is unknown. The objective wa...

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Bibliographic Details
Main Authors: Erin E Kohler, Kishore K Wary, Fei Li, Ishita Chatterjee, Norifumi Urao, Peter T Toth, Masuko Ushio-Fukai, Jalees Rehman, Changwon Park, Asrar B Malik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3875577?pdf=render