Design and development of a robotized system coupled to µCT imaging for intratumoral drug evaluation in a HCC mouse model.

Hepatocellular carcinoma (HCC) is one of the most common cancer related deaths worldwide. One of the main challenges in cancer treatment is drug delivery to target cancer cells specifically. Preclinical evaluation of intratumoral drugs in orthotopic liver cancer mouse models is difficult, as percuta...

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Bibliographic Details
Main Authors: Gaétan Bour, Fernand Martel, Laurent Goffin, Bernard Bayle, Jacques Gangloff, Marc Aprahamian, Jacques Marescaux, Jean-Marc Egly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0106675