Asymmetric Dimethylarginine, Endothelial Dysfunction and Renal Disease
L-Arginine (Arg) is oxidized to L-citrulline and nitric oxide (NO) by the action of endothelial nitric oxide synthase (NOS). In contrast, protein-incorporated Arg residues can be methylated with subsequent proteolysis giving rise to methylarginine compounds, such as asymmetric dimethylarginine (ADMA...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2012-09-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1422-0067/13/9/11288 |