An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1

An Escherichia coli Effector Protein EspF May Induce Host DNA Damage via Interaction With SMC1

Enterohemorrhagic Escherichia coli (EHEC) O157: H7 is an important foodborne pathogen that causes human diarrhea, hemorrhagic colitis, and hemolytic uremic syndrome. EspF is one of the most important effector proteins injected by the Type III Secretion System. It can target mitochondria and nucleoli...

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Bibliographic Details
Main Authors: Muqing Fu, Song Liang, Jiali Wu, Ying Hua, Hanzong Chen, Zhikai Zhang, Jinyue Liu, Xiaoxia Li, Bao Zhang, Wei Zhao, Chengsong Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Microbiology
Subjects:
EHEC (Enterohaemorrhagic E. coli)
EspF
DNA damage
SMC1
protein interactions
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.682064/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.682064/full

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