Crystallization Tendency of Pharmaceutical Glasses: Relevance to Compound Properties, Impact of Formulation Process, and Implications for Design of Amorphous Solid Dispersions

Crystallization Tendency of Pharmaceutical Glasses: Relevance to Compound Properties, Impact of Formulation Process, and Implications for Design of Amorphous Solid Dispersions

Amorphous solid dispersions (ASDs) are important formulation strategies for improving the dissolution process and oral bioavailability of poorly soluble drugs. Physical stability of a candidate drug must be clearly understood to design ASDs with superior properties. The crystallization tendency of s...

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Bibliographic Details
Main Author: Kohsaku Kawakami
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Pharmaceutics
Subjects:
pharmaceutical glass
crystallization tendency
crystallization
nucleation
milling
accelerated stability test
Online Access:https://www.mdpi.com/1999-4923/11/5/202

Internet

https://www.mdpi.com/1999-4923/11/5/202

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