Age-related changes in the daily rhythm of photoreceptor functioning and circuitry in a melatonin-proficient mouse strain.

Retinal melatonin is involved in the modulation of many important retinal functions. Our previous studies have shown that the viability of photoreceptors and ganglion cells is reduced during aging in mice that lack melatonin receptor type 1. This demonstrates that melatonin signaling is important fo...

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Bibliographic Details
Main Authors: Kenkichi Baba, Francesca Mazzoni, Sharon Owino, Susana Contreras-Alcantara, Enrica Strettoi, Gianluca Tosini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3358282?pdf=render