Increased ROS production and DNA damage in monocytes are biomarkers of aging and atherosclerosis

Increased ROS production and DNA damage in monocytes are biomarkers of aging and atherosclerosis

Abstract Background New evidence demonstrates that aging and dyslipidemia are closely associated with oxidative stress, DNA damage and apoptosis in some cells and extravascular tissues. However, in monocytes, which are naturally involved in progression and/or resolution of plaque in atherosclerosis,...

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Bibliographic Details
Main Authors: Thais A. Jacinto, Giselle S. Meireles, Ananda T. Dias, Rafaela Aires, Marcella L. Porto, Agata L. Gava, Elisardo C. Vasquez, Thiago Melo C. Pereira, Bianca P. Campagnaro, Silvana S. Meyrelles
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Biological Research
Subjects:
apoE knockout mice
Atherosclerosis
Proinflammatory cytokines
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s40659-018-0182-7

Internet

http://link.springer.com/article/10.1186/s40659-018-0182-7

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