ZNF300 tight self-regulation and functioning through DNA methylation and histone acetylation

Abstract Background Accumulating evidence demonstrates that the KRAB-ZNFs involve in various biological processes. As a typical member of KRAB-ZNFs, dysregulation of ZNF300 contributes to multiple pathologies such as leukemia and cancer. However, mechanisms underlying ZNF300 tight regulation and its...

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Bibliographic Details
Main Authors: Feng-Juan Yan, Jingyi Fan, Zan Huang, Jun-Jian Zhang
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Cell & Bioscience
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13578-017-0160-8