Polymorphisms at residue 222 of the hemagglutinin of pandemic influenza A(H1N1)pdm09: association of quasi-species to morbidity and mortality in different risk categories.

Polymorphisms at residue 222 of the hemagglutinin of pandemic influenza A(H1N1)pdm09: association of quasi-species to morbidity and mortality in different risk categories.

The D222G substitution in the hemagglutinin (HA) gene of the pandemic influenza A(H1N1)pdm09 virus has been identified as a potential virulence marker, because this change allows for virus invasion deeper into the respiratory tract. In this study, we analyzed D, G and N polymorphisms at residue 222...

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Bibliographic Details
Main Authors: Paola Cristina Resende, Fernando C Motta, Maria de Lourdes A Oliveira, Tatiana S Gregianini, Sandra B Fernandes, Ana Luisa F Cury, Maria do Carmo D Rosa, Thiago Moreno L Souza, Marilda M Siqueira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3965456?pdf=render

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http://europepmc.org/articles/PMC3965456?pdf=render

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