USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In Vitro

USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In Vitro

The ubiquitin−proteasome system is an essential regulator of several cellular pathways involving oncogenes. Deubiquitination negatively regulates target proteins or substrates linked to both hereditary and sporadic forms of cancer. The deubiquitinating enzyme ubiquitin-specific protease 14...

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Bibliographic Details
Main Authors: Kyung Ho Han, Minseok Kwak, Tae Hyeong Lee, Min-soo Park, In-ho Jeong, Min Ji Kim, Jun-O Jin, Peter Chang-Whan Lee
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
ubiquitin-specific protease 14
deubiquitinating enzyme
lung cancer
autophagy
Online Access:https://www.mdpi.com/1422-0067/20/21/5300

Internet

https://www.mdpi.com/1422-0067/20/21/5300

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