Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug.

Regulating BMI1 expression via miRNAs promote Mesenchymal to Epithelial Transition (MET) and sensitizes breast cancer cell to chemotherapeutic drug.

Polycomb group (PcG) proteinB lymphoma Mo-MLV insertion region 1 homolog (BMI1) is a transcriptional repressor that plays an important role in human carcinogenesis. MicroRNAs (miRNAs) are endogenous small non-coding RNAsthat implicate a negative regulation on gene expression. Deregulation of the exp...

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Bibliographic Details
Main Authors: Nibedita Patel, Koteswara Rao Garikapati, Venkata Krishna Kanth Makani, Ayikkara Drishya Nair, Namratha Vangara, Utpal Bhadra, Manika Pal Bhadra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5796693?pdf=render

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http://europepmc.org/articles/PMC5796693?pdf=render

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