Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans

Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans

The kynurenine pathway of tryptophan (TRP) degradation (KP) generates metabolites with effects on metabolism, immunity, and mental health. Endurance exercise training can change KP metabolites by changing the levels of KP enzymes in skeletal muscle. This leads to a metabolite pattern that favors ene...

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Bibliographic Details
Main Authors: Paula Valente-Silva, Igor Cervenka, Duarte M. S. Ferreira, Jorge C. Correia, Sebastian Edman, Oscar Horwath, Benjamin Heng, Sharron Chow, Kelly R. Jacobs, Gilles J. Guillemin, Eva Blomstrand, Jorge L. Ruas
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Metabolites
Subjects:
dietary supplements
exercise
tryptophan
kynurenine metabolites
energy metabolism
skeletal muscle
Online Access:https://www.mdpi.com/2218-1989/11/8/508

Internet

https://www.mdpi.com/2218-1989/11/8/508

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