Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies

<p>Abstract</p> <p>Background</p> <p>Epithelial cell adhesion molecule (EpCAM) is frequently and highly expressed on human carcinomas. The emerging role of EpCAM as a signalling receptor and activator of the wnt pathway, and its expression on tumor-initiating cells, fur...

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Main Authors: Pflanz Stefan, Mangold Susanne, Rau Doris, Kvesic Majk, Murr Alexander, Münz Markus, Lumsden John, Volkland Jörg, Fagerberg Jan, Riethmüller Gert, Rüttinger Dominik, Kufer Peter, Baeuerle Patrick A, Raum Tobias
Format: Article
Language:English
Published: BMC 2010-11-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/10/1/44