Lipopolysaccharides promote pulmonary fibrosis in silicosis through the aggravation of apoptosis and inflammation in alveolar macrophages

Alveolar macrophages (AMs) play an important defensive role by removing dust and bacteria from alveoli. Apoptosis of AMs is associated with lung fibrosis; however, the relationship between this apoptotic event and environmental factors, such as the presence of lipopolysaccharides (LPSs) in the workp...

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Bibliographic Details
Main Authors: Tan Shiyi, Yang Shang, Chen Mingke, Wang Yurun, Zhu Li, Sun Zhiqian, Chen Shi
Format: Article
Language:English
Published: De Gruyter 2020-08-01
Series:Open Life Sciences
Subjects:
lps
Online Access:https://doi.org/10.1515/biol-2020-0061