Dentinogenic effects of extracted dentin matrix components digested with matrix metalloproteinases

Abstract Dentin is primarily composed of hydroxyapatite crystals within a rich organic matrix. The organic matrix comprises collagenous structural components, within which a variety of bioactive molecules are sequestered. During caries progression, dentin is degraded by acids and enzymes derived fro...

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Bibliographic Details
Main Authors: Motoki Okamoto, Yusuke Takahashi, Shungo Komichi, Paul R. Cooper, Mikako Hayashi
Format: Article
Language:English
Published: Nature Publishing Group 2018-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-29112-3