Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels.

Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels.

During myogenesis several transcription factors and regulators of protein synthesis and assembly are rapidly degraded by the ubiquitin-proteasome system (UPS). Given the potential role of the deubiquitinating enzyme (DUB) ataxin-3 in the UPS, and the high expression of the murine ataxin-3 homolog in...

Full description

Bibliographic Details
Main Authors: Maria do Carmo Costa, Fernanda Bajanca, Ana-João Rodrigues, Ricardo J Tomé, Garry Corthals, Sandra Macedo-Ribeiro, Henry L Paulson, Elsa Logarinho, Patrícia Maciel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2909204?pdf=render

Internet

http://europepmc.org/articles/PMC2909204?pdf=render

Similar Items