A classification model for distinguishing copy number variants from cancer-related alterations

<p>Abstract</p> <p>Background</p> <p>Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in comparative genomic hybridization (CGH) analyses of tumors. In order to...

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Bibliographic Details
Main Authors: Olshen Adam B, Nanjangud Gouri, Ostrovnaya Irina
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/297