De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation

De novo lipogenesis in the differentiating human adipocyte can provide all fatty acids necessary for maturation

The primary products of de novo lipogenesis (DNL) are saturated fatty acids, which confer adverse cellular effects. Human adipocytes differentiated with no exogenous fat accumulated triacylglycerol (TG) in lipid droplets and differentiated normally. TG composition showed the products of DNL (saturat...

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Bibliographic Details
Main Authors: Jennifer M. Collins, Matt J. Neville, Katherine E. Pinnick, Leanne Hodson, Bente Ruyter, Theo H. van Dijk, Dirk-Jan Reijngoud, Mark D. Fielding, Keith N. Frayn
Format: Article
Language:English
Published: Elsevier 2011-09-01
Series:Journal of Lipid Research
Subjects:
desaturation
elongation
fatty acid synthesis
mass isotopomer
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408594

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http://www.sciencedirect.com/science/article/pii/S0022227520408594

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