CARD14 expression in dermal endothelial cells in psoriasis.

Mutations in the caspase recruitment domain, family member 14 (CARD14) gene have recently been described in psoriasis patients, and explain the psoriasis susceptibility locus 2 (PSORS2). CARD14 is a scaffolding protein that regulates NF-κB activation, and psoriasis-associated CARD14 mutations lead t...

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Bibliographic Details
Main Authors: Jamie L Harden, Steven M Lewis, Katherine C Pierson, Mayte Suárez-Fariñas, Tim Lentini, Francesca S Ortenzio, Lisa C Zaba, Raphaela Goldbach-Mansky, Anne M Bowcock, Michelle A Lowes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4219711?pdf=render