CARD14 expression in dermal endothelial cells in psoriasis.
Mutations in the caspase recruitment domain, family member 14 (CARD14) gene have recently been described in psoriasis patients, and explain the psoriasis susceptibility locus 2 (PSORS2). CARD14 is a scaffolding protein that regulates NF-κB activation, and psoriasis-associated CARD14 mutations lead t...
Main Authors: | Jamie L Harden, Steven M Lewis, Katherine C Pierson, Mayte Suárez-Fariñas, Tim Lentini, Francesca S Ortenzio, Lisa C Zaba, Raphaela Goldbach-Mansky, Anne M Bowcock, Michelle A Lowes |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4219711?pdf=render |
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