Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells[S]

Perilipin 5 and liver fatty acid binding protein function to restore quiescence in mouse hepatic stellate cells[S]

Hepatic stellate cell (HSC) activation occurs along with decreased Perilipin5 (Plin5) and liver fatty acid-binding protein (L-Fabp) expression and coincident lipid droplet (LD) depletion. Conversely, the activated phenotype is reversible in WT HSCs upon forced expression of Plin5. Here, we asked if...

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Bibliographic Details
Main Authors: Jianguo Lin, Shizhong Zheng, Alan D. Attie, Mark P. Keller, David A. Bernlohr, William S. Blaner, Elizabeth P. Newberry, Nicholas O. Davidson, Anping Chen
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Journal of Lipid Research
Subjects:
lipid droplets
perilipins
fatty acid-binding proteins
lipid metabolism
stellate cell activation
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033131X

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http://www.sciencedirect.com/science/article/pii/S002222752033131X

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