Lack of Major Involvement of Common CYP2C Gene Polymorphisms in the Risk of Developing Cross-Hypersensitivity to NSAIDs

Lack of Major Involvement of Common CYP2C Gene Polymorphisms in the Risk of Developing Cross-Hypersensitivity to NSAIDs

Cross-hypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) is a relatively common, non-allergic, adverse drug event triggered by two or more chemically unrelated NSAIDs. Current evidence point to COX-1 inhibition as one of the main factors in its etiopathogenesis. Evidence also suggest...

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Bibliographic Details
Main Authors: Yolanda Macías, Jesús M. García-Menaya, Manuel Martí, Concepción Cordobés, Raquel Jurado-Escobar, José A. Cornejo-García, María J. Torres, Natalia Blanca-López, Gabriela Canto, Miguel Blanca, José J. Laguna, Joan Bartra, Ana Rosado, Javier Fernández, Elena García-Martín, José A. G. Agúndez
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
CYP2C8
CYP2C9
CYP2C19
NSAID
polymorphisms
hypersensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.648262/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.648262/full

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